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Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break
Tumor suppressor p53-binding protein 1 (53BP1) is a DNA repair protein essential for the detection, assessment, and resolution of DNA double strand breaks (DSBs). The presence of a DSB is signaled to 53BP1 via a local histone modification cascade that triggers the binding of 53BP1 dimers to chromati...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7666136/ https://ncbi.nlm.nih.gov/pubmed/33188174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19504-3 |
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