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SET8 methyltransferase activity during the DNA double-strand break response is required for recruitment of 53BP1
DNA double-strand breaks (DSBs) activate a signaling pathway known as the DNA damage response (DDR) which via protein–protein interactions and post-translational modifications recruit signaling proteins, such as 53BP1, to chromatin flanking the lesion. Depletion of the SET8 methyltransferase prevent...
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| Veröffentlicht in: | EMBO Rep |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253490/ https://ncbi.nlm.nih.gov/pubmed/25252681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439434 |
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