SET8 methyltransferase activity during the DNA double-strand break response is required for recruitment of 53BP1

DNA double-strand breaks (DSBs) activate a signaling pathway known as the DNA damage response (DDR) which via protein–protein interactions and post-translational modifications recruit signaling proteins, such as 53BP1, to chromatin flanking the lesion. Depletion of the SET8 methyltransferase prevent...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:EMBO Rep
Main Authors: Dulev, Stanimir, Tkach, Johnny, Lin, Sichun, Batada, Nizar N
Formáid: Artigo
Teanga:Inglês
Foilsithe: BlackWell Publishing Ltd 2014
Ábhair:
Scientific Reports
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253490/
https://ncbi.nlm.nih.gov/pubmed/25252681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439434
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla