The Capture of a Disabled Proteasome Identifies Erg25 as a Substrate for Endoplasmic Reticulum Associated Degradation

Studies in the yeast Saccharomyces cerevisiae have helped define mechanisms underlying the activity of the ubiquitin–proteasome system (UPS), uncover the proteasome assembly pathway, and link the UPS to the maintenance of cellular homeostasis. However, the spectrum of UPS substrates is incompletely...

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Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Buck, Teresa M., Zeng, Xuemei, Cantrell, Pamela S., Cattley, Richard T., Hasanbasri, Zikri, Yates, Megan E., Nguyen, Diep, Yates, Nathan A., Brodsky, Jeffrey L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664122/
https://ncbi.nlm.nih.gov/pubmed/32868373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002050
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