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Molecular chaperones and substrate ubiquitination control the efficiency of endoplasmic reticulum-associated degradation
The endoplasmic reticulum (ER) must contend with a large protein flux, which is especially notable in cells dedicated to secreting hormone-regulated gene products. Because of the complexity of the protein folding pathway and the potential for genetic or stochastic errors, a significant percentage of...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071497/ https://ncbi.nlm.nih.gov/pubmed/21029298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2010.01273.x |
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