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A Cleavable C(2)-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes

[Image: see text] Bioorthogonal chemistry is bridging the divide between static chemical connectivity and the dynamic physiologic regulation of molecular state, enabling in situ transformations that drive multiple technologies. In spite of maturing mechanistic understanding and new bioorthogonal bon...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wilkovitsch, Martin, Haider, Maximilian, Sohr, Barbara, Herrmann, Barbara, Klubnick, Jenna, Weissleder, Ralph, Carlson, Jonathan C. T., Mikula, Hannes
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662912/
https://ncbi.nlm.nih.gov/pubmed/33119297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c07922
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