Efficient low-cost preparation of trans-cyclooctenes using a simplified flow setup for photoisomerization

ABSTRACT: Bioorthogonal ligations have emerged as highly versatile chemical tools for biomedical research. The exceptionally fast reaction between 1,2,4,5-tetrazines and trans-cyclooctenes (TCOs), also known as tetrazine ligation, is frequently used in this regard. Growing numbers of applications fo...

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Bibliografiske detaljer
Udgivet i:Monatsh Chem
Main Authors: Svatunek, Dennis, Denk, Christoph, Rosecker, Veronika, Sohr, Barbara, Hametner, Christian, Allmaier, Günter, Fröhlich, Johannes, Mikula, Hannes
Format: Artigo
Sprog:Inglês
Udgivet: Springer Vienna 2016
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785212/
https://ncbi.nlm.nih.gov/pubmed/27069284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1668-z
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