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A Cleavable C(2)-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes

[Image: see text] Bioorthogonal chemistry is bridging the divide between static chemical connectivity and the dynamic physiologic regulation of molecular state, enabling in situ transformations that drive multiple technologies. In spite of maturing mechanistic understanding and new bioorthogonal bon...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Wilkovitsch, Martin, Haider, Maximilian, Sohr, Barbara, Herrmann, Barbara, Klubnick, Jenna, Weissleder, Ralph, Carlson, Jonathan C. T., Mikula, Hannes
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662912/
https://ncbi.nlm.nih.gov/pubmed/33119297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c07922
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