A Cleavable C(2)-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes

[Image: see text] Bioorthogonal chemistry is bridging the divide between static chemical connectivity and the dynamic physiologic regulation of molecular state, enabling in situ transformations that drive multiple technologies. In spite of maturing mechanistic understanding and new bioorthogonal bon...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Wilkovitsch, Martin, Haider, Maximilian, Sohr, Barbara, Herrmann, Barbara, Klubnick, Jenna, Weissleder, Ralph, Carlson, Jonathan C. T., Mikula, Hannes
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662912/
https://ncbi.nlm.nih.gov/pubmed/33119297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c07922
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