Osteoprotegerin Prevents Intracranial Aneurysm Progression by Promoting Collagen Biosynthesis and Vascular Smooth Muscle Cell Proliferation

BACKGROUND: Decreased extracellular matrix formation and few vascular smooth muscle cells (VSMCs) in cerebral vascular walls are the main characteristics of intracranial aneurysm (IA) pathogenesis. Recently, osteoprotegerin was reported to activate collagen biosynthesis and VSMC proliferation via th...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Miyata, Takeshi, Minami, Manabu, Kataoka, Hiroharu, Hayashi, Kosuke, Ikedo, Taichi, Yang, Tao, Yamamoto, Yu, Yokode, Masayuki, Miyamoto, Susumu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660769/
https://ncbi.nlm.nih.gov/pubmed/32856519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015731
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