Dipeptidyl Peptidase‐4 Inhibitor Anagliptin Prevents Intracranial Aneurysm Growth by Suppressing Macrophage Infiltration and Activation

BACKGROUND: Chronic inflammation plays a key role in the pathogenesis of intracranial aneurysms (IAs). DPP‐4 (dipeptidyl peptidase‐4) inhibitors have anti‐inflammatory effects, including suppressing macrophage infiltration, in various inflammatory models. We examined whether a DPP‐4 inhibitor, anagl...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Ikedo, Taichi, Minami, Manabu, Kataoka, Hiroharu, Hayashi, Kosuke, Nagata, Manabu, Fujikawa, Risako, Higuchi, Sei, Yasui, Mika, Aoki, Tomohiro, Fukuda, Miyuki, Yokode, Masayuki, Miyamoto, Susumu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669147/
https://ncbi.nlm.nih.gov/pubmed/28630262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004777
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