The Prostaglandin E2 Receptor EP4 Regulates Obesity-Related Inflammation and Insulin Sensitivity

With increasing body weight, macrophages accumulate in adipose tissue. There, activated macrophages secrete numerous proinflammatory cytokines and chemokines, giving rise to chronic inflammation and insulin resistance. Prostaglandin E(2) suppresses macrophage activation via EP4; however, the role of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yasui, Mika, Tamura, Yukinori, Minami, Manabu, Higuchi, Sei, Fujikawa, Risako, Ikedo, Taichi, Nagata, Manabu, Arai, Hidenori, Murayama, Toshinori, Yokode, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550358/
https://ncbi.nlm.nih.gov/pubmed/26308623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136304
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