Sphingosine kinase‐1 inhibition sensitizes curcumin‐induced growth inhibition and apoptosis in ovarian cancer cells

Recent published studies suggest that increasing levels of ceramides enhance the chemo‐sensitivity of curcumin. Using in vitro approaches, we analyzed the impact of sphingosine kinase‐1 (SphK‐1) inhibition on ceramide production, and evaluated SphK1 inhibitor II (SKI‐II) as a potential curcumin chem...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Yang, Yan‐li, Ji, Chao, Cheng, Lei, He, Li, Lu, Chun‐cheng, Wang, Rong, Bi, Zhi‐gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2012
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659178/
https://ncbi.nlm.nih.gov/pubmed/22594559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02335.x
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