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Sphingosine kinase‐1 inhibition sensitizes curcumin‐induced growth inhibition and apoptosis in ovarian cancer cells

Recent published studies suggest that increasing levels of ceramides enhance the chemo‐sensitivity of curcumin. Using in vitro approaches, we analyzed the impact of sphingosine kinase‐1 (SphK‐1) inhibition on ceramide production, and evaluated SphK1 inhibitor II (SKI‐II) as a potential curcumin chem...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Yang, Yan‐li, Ji, Chao, Cheng, Lei, He, Li, Lu, Chun‐cheng, Wang, Rong, Bi, Zhi‐gang
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659178/
https://ncbi.nlm.nih.gov/pubmed/22594559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02335.x
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