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Sphingosine kinase‐1 inhibition sensitizes curcumin‐induced growth inhibition and apoptosis in ovarian cancer cells

Recent published studies suggest that increasing levels of ceramides enhance the chemo‐sensitivity of curcumin. Using in vitro approaches, we analyzed the impact of sphingosine kinase‐1 (SphK‐1) inhibition on ceramide production, and evaluated SphK1 inhibitor II (SKI‐II) as a potential curcumin chem...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Yang, Yan‐li, Ji, Chao, Cheng, Lei, He, Li, Lu, Chun‐cheng, Wang, Rong, Bi, Zhi‐gang
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659178/
https://ncbi.nlm.nih.gov/pubmed/22594559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02335.x
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