Sphingosine kinase‐1 inhibition sensitizes curcumin‐induced growth inhibition and apoptosis in ovarian cancer cells

Recent published studies suggest that increasing levels of ceramides enhance the chemo‐sensitivity of curcumin. Using in vitro approaches, we analyzed the impact of sphingosine kinase‐1 (SphK‐1) inhibition on ceramide production, and evaluated SphK1 inhibitor II (SKI‐II) as a potential curcumin chem...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Yang, Yan‐li, Ji, Chao, Cheng, Lei, He, Li, Lu, Chun‐cheng, Wang, Rong, Bi, Zhi‐gang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659178/
https://ncbi.nlm.nih.gov/pubmed/22594559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02335.x
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