Sphingosine kinase‐1 inhibition sensitizes curcumin‐induced growth inhibition and apoptosis in ovarian cancer cells

Recent published studies suggest that increasing levels of ceramides enhance the chemo‐sensitivity of curcumin. Using in vitro approaches, we analyzed the impact of sphingosine kinase‐1 (SphK‐1) inhibition on ceramide production, and evaluated SphK1 inhibitor II (SKI‐II) as a potential curcumin chem...

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Vydáno v:Cancer Sci
Hlavní autoři: Yang, Yan‐li, Ji, Chao, Cheng, Lei, He, Li, Lu, Chun‐cheng, Wang, Rong, Bi, Zhi‐gang
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2012
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659178/
https://ncbi.nlm.nih.gov/pubmed/22594559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02335.x
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