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Predicting antibody affinity changes upon mutations by combining multiple predictors

Antibodies are proteins working in our immune system with high affinity and specificity for target antigens, making them excellent tools for both biotherapeutic and bioengineering applications. The prediction of antibody affinity changes upon mutations ([Formula: see text] ) is important for antibod...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kurumida, Yoichi, Saito, Yutaka, Kameda, Tomoshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658247/
https://ncbi.nlm.nih.gov/pubmed/33177627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76369-8
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