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Predicting antibody affinity changes upon mutations by combining multiple predictors

Antibodies are proteins working in our immune system with high affinity and specificity for target antigens, making them excellent tools for both biotherapeutic and bioengineering applications. The prediction of antibody affinity changes upon mutations ([Formula: see text] ) is important for antibod...

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Foilsithe in:Sci Rep
Main Authors: Kurumida, Yoichi, Saito, Yutaka, Kameda, Tomoshi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658247/
https://ncbi.nlm.nih.gov/pubmed/33177627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76369-8
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