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Predicting antibody affinity changes upon mutations by combining multiple predictors

Antibodies are proteins working in our immune system with high affinity and specificity for target antigens, making them excellent tools for both biotherapeutic and bioengineering applications. The prediction of antibody affinity changes upon mutations ([Formula: see text] ) is important for antibod...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kurumida, Yoichi, Saito, Yutaka, Kameda, Tomoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658247/
https://ncbi.nlm.nih.gov/pubmed/33177627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76369-8
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