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Predicting antibody affinity changes upon mutations by combining multiple predictors

Antibodies are proteins working in our immune system with high affinity and specificity for target antigens, making them excellent tools for both biotherapeutic and bioengineering applications. The prediction of antibody affinity changes upon mutations ([Formula: see text] ) is important for antibod...

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Publicat a:Sci Rep
Autors principals: Kurumida, Yoichi, Saito, Yutaka, Kameda, Tomoshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658247/
https://ncbi.nlm.nih.gov/pubmed/33177627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76369-8
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