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Predicting protein thermostability changes from sequence upon multiple mutations

Motivation: A basic question in protein science is to which extent mutations affect protein thermostability. This knowledge would be particularly relevant for engineering thermostable enzymes. In several experimental approaches, this issue has been serendipitously addressed. It would be therefore co...

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Detalhes bibliográficos
Main Authors: Montanucci, Ludovica, Fariselli, Piero, Martelli, Pier Luigi, Casadio, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718644/
https://ncbi.nlm.nih.gov/pubmed/18586713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn166
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