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Molecular mapping of transmembrane mechanotransduction through the β1 integrin–CD98hc–TRPV4 axis

One of the most rapid (less than 4 ms) transmembrane cellular mechanotransduction events involves activation of transient receptor potential vanilloid 4 (TRPV4) ion channels by mechanical forces transmitted across cell surface β1 integrin receptors on endothelial cells, and the transmembrane solute...

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Detalles Bibliográficos
Publicado en:J Cell Sci
Autores principales: Potla, Ratnakar, Hirano-Kobayashi, Mariko, Wu, Hao, Chen, Hong, Mammoto, Akiko, Matthews, Benjamin D., Ingber, Donald E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657480/
https://ncbi.nlm.nih.gov/pubmed/32989042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.248823
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