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Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface β1 integrins

Integrins are ubiquitous transmembrane mechanoreceptors that elicit changes in intracellular biochemistry in response to mechanical force application, but these alterations generally proceed over seconds to minutes. Stress-sensitive ion channels represent another class of mechanoreceptors that are a...

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Autori principali: Matthews, Benjamin D., Thodeti, Charles K., Tytell, Jessica D., Mammoto, Akiko, Overby, Darryl R., Ingber, Donald E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147167/
https://ncbi.nlm.nih.gov/pubmed/20725677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ib00034e
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