Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy

Tumor vessels are characterized by abnormal morphology and hyper-permeability that together cause inefficient delivery of chemotherapeutic agents. Although VEGF has been established as a critical regulator of tumor angiogenesis, the role of mechanical signaling in the regulation of tumor vasculature...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncogene
Egile Nagusiak: Adapala, Ravi K., Thoppil, Roslin J., Ghosh, Kaustabh, Cappelli, Holly, Dudley, Andrew C., Paruchuri, Sailaja, Keshamouni, Venkateshwar, Klagsbrun, Michael, Meszaros, J. Gary, Chilian, William M., Ingber, Donald E., Thodeti, Charles K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948740/
https://ncbi.nlm.nih.gov/pubmed/25867067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.83
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