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TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals

The phenotypic switch underlying the differentiation of cardiac fibroblasts into hypersecretory myofibroblasts is critical for cardiac remodeling following myocardial infarction. Myofibroblasts facilitate wound repair in the myocardium by secreting and organizing extracellular matrix (ECM) during th...

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Bibliografische gegevens
Hoofdauteurs: Adapala, Ravi K., Thoppil, Roslin, Luther, Daniel J., Paruchuri, Sailaja, Meszaros, J. Gary, Chilian, William M., Thodeti, Charles K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935769/
https://ncbi.nlm.nih.gov/pubmed/23142541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.10.016
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