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TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin to integrin signaling

Cyclic mechanical strain produced by pulsatile blood flow regulates the orientation of endothelial cells lining blood vessels, and influences critical processes such as angiogenesis. Mechanical stimulation of stretch-activated calcium channels is known to mediate this reorientation response, however...

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Detalhes bibliográficos
Main Authors: Thodeti, Charles K., Matthews, Benjamin, Ravi, Arvind, Mammoto, Akiko, Ghosh, Kaustabh, Bracha, Abigail L., Ingber, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754067/
https://ncbi.nlm.nih.gov/pubmed/19359599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.192930
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