Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherence‐related genes

Hedgehog signal is re‐activated in several cancers. In this study, we examined the role of Gli3 on malignant phenotype of tumorigenicity for colorectal cancer and its relationship with p53, WNT and ERK/AKT signals. Gli3 expression was detected in HT29 and SW480 (p53‐mutant) cells, but not in DLD‐1 (...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Iwasaki, Hironori, Nakano, Kenji, Shinkai, Kentaro, Kunisawa, Yumi, Hirahashi, Minako, Oda, Yoshinao, Onishi, Hideya, Katano, Mitsuo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2013
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657255/
https://ncbi.nlm.nih.gov/pubmed/23176625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12073
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