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Reoxygenation from chronic hypoxia promotes metastatic processes in pancreatic cancer through the Hedgehog signaling

Pancreatic ductal adenocarcinoma (PDAC) is among the most deadly types of malignancies because of its high ability to metastasize. PDAC is thought to be under hypoxic condition. Therefore, to investigate the mechanism of metastatic processes, chronic-hypoxia-resistant PDAC cells were newly generated...

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Publicado en:Cancer Sci
Main Authors: Morifuji, Yoshihiro, Onishi, Hideya, Iwasaki, Hironori, Imaizumi, Akira, Nakano, Kenji, Tanaka, Masao, Katano, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317936/
https://ncbi.nlm.nih.gov/pubmed/24397700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12348
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