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Reoxygenation from chronic hypoxia promotes metastatic processes in pancreatic cancer through the Hedgehog signaling

Pancreatic ductal adenocarcinoma (PDAC) is among the most deadly types of malignancies because of its high ability to metastasize. PDAC is thought to be under hypoxic condition. Therefore, to investigate the mechanism of metastatic processes, chronic-hypoxia-resistant PDAC cells were newly generated...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Morifuji, Yoshihiro, Onishi, Hideya, Iwasaki, Hironori, Imaizumi, Akira, Nakano, Kenji, Tanaka, Masao, Katano, Mitsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317936/
https://ncbi.nlm.nih.gov/pubmed/24397700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12348
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