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Ataxia–telangiectasia mutated kinase‐mediated upregulation of NKG2D ligands on leukemia cells by resveratrol results in enhanced natural killer cell susceptibility

The powerful activating receptor NKG2D is expressed by natural killer (NK) cells and promotes cytotoxic lysis of cancer cells expressing NKG2D ligands (NKG2D‐Ls). We report the effective induction of NKG2D‐Ls, achieved with the naturally occurring polyphenol resveratrol, in a broad range of leukemia...

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Foilsithe in:Cancer Sci
Main Authors: Luis Espinoza, J., Takami, Akiyoshi, Trung, Ly Q., Nakao, Shinji
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657230/
https://ncbi.nlm.nih.gov/pubmed/23445485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12141
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