A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers

Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide and is etiologically linked to several cancers, including cervical and genital cancers. NKG2D, an activating receptor expressed by NK cells, plays an important role in cancer immune-surveillance. We analyzed the impac...

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Vydáno v:Sci Rep
Hlavní autoři: Espinoza, J. Luis, Nguyen, Viet H., Ichimura, Hiroshi, Pham, Trang T. T., Nguyen, Cuong H., Pham, Thuc V., Elbadry, Mahmoud I., Yoshioka, Katsuji, Tanaka, Junji, Trung, Ly Q., Takami, Akiyoshi, Nakao, Shinji
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5172372/
https://ncbi.nlm.nih.gov/pubmed/27995954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39231
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