A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers

Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide and is etiologically linked to several cancers, including cervical and genital cancers. NKG2D, an activating receptor expressed by NK cells, plays an important role in cancer immune-surveillance. We analyzed the impac...

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Pubblicato in:Sci Rep
Autori principali: Espinoza, J. Luis, Nguyen, Viet H., Ichimura, Hiroshi, Pham, Trang T. T., Nguyen, Cuong H., Pham, Thuc V., Elbadry, Mahmoud I., Yoshioka, Katsuji, Tanaka, Junji, Trung, Ly Q., Takami, Akiyoshi, Nakao, Shinji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5172372/
https://ncbi.nlm.nih.gov/pubmed/27995954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39231
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