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Resveratrol Induces Cell Cycle Arrest and Apoptosis in Malignant NK Cells via JAK2/STAT3 Pathway Inhibition

Natural killer (NK) cell malignancies, particularly aggressive NK cell leukaemias and lymphomas, have poor prognoses. Although recent regimens with L-asparaginase substantially improved outcomes, novel therapeutic approaches are still needed to enhance clinical response. Resveratrol, a naturally occ...

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Detalhes bibliográficos
Main Authors: Quoc Trung, Ly, Espinoza, J. Luis, Takami, Akiyoshi, Nakao, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555980/
https://ncbi.nlm.nih.gov/pubmed/23372833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055183
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