Paraptosis Cell Death Induction by the Thiamine Analog Benfotiamine in Leukemia Cells

Benfotiamine is a synthetic thiamine analogue that stimulates transketolase, a cellular enzyme essential for glucose metabolism. Currently, benfotiamine is used to treat diabetic neuropathy. We recently reported that oral benfotiamine induced a temporary but remarkable recovery from acute myeloid le...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sugimori, Naomi, Espinoza, J. Luis, Trung, Ly Quoc, Takami, Akiyoshi, Kondo, Yukio, An, Dao Thi, Sasaki, Motoko, Wakayama, Tomohiko, Nakao, Shinji
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388699/
https://ncbi.nlm.nih.gov/pubmed/25849583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120709
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