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Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation
Aging leads to functional decline of the hematopoietic system, manifested by an increased incidence of hematological disease in the elderly. Deterioration of hematopoietic integrity with age originates in part from the degraded functionality of hematopoietic stem cells (HSCs). Here, we review recent...
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| Опубликовано в: : | Trends Mol Med |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7657013/ https://ncbi.nlm.nih.gov/pubmed/31109796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2019.04.006 |
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