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Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation

Aging leads to functional decline of the hematopoietic system, manifested by an increased incidence of hematological disease in the elderly. Deterioration of hematopoietic integrity with age originates in part from the degraded functionality of hematopoietic stem cells (HSCs). Here, we review recent...

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Bibliografische gegevens
Gepubliceerd in:Trends Mol Med
Hoofdauteurs: Verovskaya, Evgenia V., Dellorusso, Paul V., Passegué, Emmanuelle
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657013/
https://ncbi.nlm.nih.gov/pubmed/31109796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2019.04.006
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