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Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation

Aging leads to functional decline of the hematopoietic system, manifested by an increased incidence of hematological disease in the elderly. Deterioration of hematopoietic integrity with age originates in part from the degraded functionality of hematopoietic stem cells (HSCs). Here, we review recent...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Mol Med
Prif Awduron: Verovskaya, Evgenia V., Dellorusso, Paul V., Passegué, Emmanuelle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657013/
https://ncbi.nlm.nih.gov/pubmed/31109796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2019.04.006
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