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Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions
While young blood can restore many aged tissues, its effects on the aged blood system itself and old hematopoietic stem cells (HSCs) have not been determined. Here, we used transplantation, parabiosis, plasma transfer, exercise, calorie restriction, and aging mutant mice to understand the effects of...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8155813/ https://ncbi.nlm.nih.gov/pubmed/34032859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20210223 |
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