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Single cell analysis of neonatal HSC ontogeny reveals gradual and uncoordinated transcriptional reprogramming that begins before birth
Fetal and adult hematopoietic stem cells (HSCs) have distinct proliferation rates, lineage biases, gene expression profiles and gene dependencies. While these differences are widely recognized, it is not clear how the transition from fetal to adult identity is coordinated. Here we show that murine H...
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| Udgivet i: | Cell Stem Cell |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7655695/ https://ncbi.nlm.nih.gov/pubmed/32822583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.08.001 |
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