A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats

Non-alcoholic steatohepatitis (NASH) is a recognized risk factor for liver fibrosis and malignancies, and is associated with features of metabolic syndrome, such as obesity and insulin resistance (IR). We previously demonstrated that the disturbance of connexin 32 (Cx32), a gap junctional protein of...

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Dettagli Bibliografici
Pubblicato in:Arch Toxicol
Autori principali: Naiki-Ito, Aya, Kato, Hiroyuki, Naiki, Taku, Yeewa, Ranchana, Aoyama, Yoshinaga, Nagayasu, Yuko, Suzuki, Shugo, Inaguma, Shingo, Takahashi, Satoru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
Soggetti:
Organ Toxicity and Mechanisms
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655588/
https://ncbi.nlm.nih.gov/pubmed/32833043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02873-5
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