A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats

Non-alcoholic steatohepatitis (NASH) is a recognized risk factor for liver fibrosis and malignancies, and is associated with features of metabolic syndrome, such as obesity and insulin resistance (IR). We previously demonstrated that the disturbance of connexin 32 (Cx32), a gap junctional protein of...

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Bibliografische gegevens
Gepubliceerd in:Arch Toxicol
Hoofdauteurs: Naiki-Ito, Aya, Kato, Hiroyuki, Naiki, Taku, Yeewa, Ranchana, Aoyama, Yoshinaga, Nagayasu, Yuko, Suzuki, Shugo, Inaguma, Shingo, Takahashi, Satoru
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2020
Onderwerpen:
Organ Toxicity and Mechanisms
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655588/
https://ncbi.nlm.nih.gov/pubmed/32833043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02873-5
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