A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats

Non-alcoholic steatohepatitis (NASH) is a recognized risk factor for liver fibrosis and malignancies, and is associated with features of metabolic syndrome, such as obesity and insulin resistance (IR). We previously demonstrated that the disturbance of connexin 32 (Cx32), a gap junctional protein of...

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Bibliografiske detaljer
Udgivet i:Arch Toxicol
Main Authors: Naiki-Ito, Aya, Kato, Hiroyuki, Naiki, Taku, Yeewa, Ranchana, Aoyama, Yoshinaga, Nagayasu, Yuko, Suzuki, Shugo, Inaguma, Shingo, Takahashi, Satoru
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Organ Toxicity and Mechanisms
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655588/
https://ncbi.nlm.nih.gov/pubmed/32833043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02873-5
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