A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats

Non-alcoholic steatohepatitis (NASH) is a recognized risk factor for liver fibrosis and malignancies, and is associated with features of metabolic syndrome, such as obesity and insulin resistance (IR). We previously demonstrated that the disturbance of connexin 32 (Cx32), a gap junctional protein of...

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Dades bibliogràfiques
Publicat a:Arch Toxicol
Autors principals: Naiki-Ito, Aya, Kato, Hiroyuki, Naiki, Taku, Yeewa, Ranchana, Aoyama, Yoshinaga, Nagayasu, Yuko, Suzuki, Shugo, Inaguma, Shingo, Takahashi, Satoru
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
Matèries:
Organ Toxicity and Mechanisms
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655588/
https://ncbi.nlm.nih.gov/pubmed/32833043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02873-5
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