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Cohesin residency determines chromatin loop patterns

The organization of chromatin into higher order structures is essential for chromosome segregation, the repair of DNA-damage, and the regulation of gene expression. Using Micro-C XL to detect chromosomal interactions, we observed the pervasive presence of cohesin-dependent loops with defined positio...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Costantino, Lorenzo, Hsieh, Tsung-Han S, Lamothe, Rebecca, Darzacq, Xavier, Koshland, Douglas
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655110/
https://ncbi.nlm.nih.gov/pubmed/33170773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59889
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