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The Yin and Yang of R-loop Biology

RNA performs diverse functions in cells, directing translation, modulating transcription and catalyzing enzymatic reactions. Remarkably RNA can also anneal to its genomic template co- or post-transcriptionally to generate an RNA-DNA hybrid and a displaced single-stranded DNA. These unusual nucleic a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Curr Opin Cell Biol
Auteurs principaux: Costantino, Lorenzo, Koshland, Douglas
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522345/
https://ncbi.nlm.nih.gov/pubmed/25938907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2015.04.008
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