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S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation
R loops form when transcripts hybridize to homologous DNA on chromosomes, yielding a DNA:RNA hybrid and a displaced DNA single strand. R loops impact the genome of many organisms, regulating chromosome stability, gene expression, and DNA repair. Understanding the parameters dictating R-loop formatio...
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| Pubblicato in: | Genes Dev |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4911931/ https://ncbi.nlm.nih.gov/pubmed/27298336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.280834.116 |
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