A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics

The enzyme kynurenine 3-monooxygenase (KMO) operates at a critical branch-point in the kynurenine pathway (KP), the major route of tryptophan metabolism. As the KP has been implicated in the pathogenesis of several human diseases, KMO and other enzymes that control metabolic flux through the pathway...

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Udgivet i:PLoS Genet
Main Authors: Maddison, Daniel C., Alfonso-Núñez, Mónica, Swaih, Aisha M., Breda, Carlo, Campesan, Susanna, Allcock, Natalie, Straatman-Iwanowska, Anna, Kyriacou, Charalambos P., Giorgini, Flaviano
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654755/
https://ncbi.nlm.nih.gov/pubmed/33170836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009129
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