TAMI-35. AUTOPHAGY MEDIATED LIPID CATABOLISM FACILITATES GLIOMA PROGRESSION TO OVERCOME BIOENERGETIC CRISIS

Activation of mTORC1 plays a significant role in cancer development and progression. However, the metabolic mechanisms to sustain mTORC1 activation in stressed cancer cells are still underappreciated. Autophagy, one downstream process of mTORC1, is proposed to be suppressed under the condition of mT...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Wang, Chenran, Haas, Michael, Yeo, Syn, Paul, Ritama, Yang, Fuchun, Vallabhapurapu, Subrahmanya, Qi, Xiaoyang, Plas, David R, Guan, Jun-Lin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651293/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.923
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