TAMI-35. AUTOPHAGY MEDIATED LIPID CATABOLISM FACILITATES GLIOMA PROGRESSION TO OVERCOME BIOENERGETIC CRISIS

Activation of mTORC1 plays a significant role in cancer development and progression. However, the metabolic mechanisms to sustain mTORC1 activation in stressed cancer cells are still underappreciated. Autophagy, one downstream process of mTORC1, is proposed to be suppressed under the condition of mT...

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Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Wang, Chenran, Haas, Michael, Yeo, Syn, Paul, Ritama, Yang, Fuchun, Vallabhapurapu, Subrahmanya, Qi, Xiaoyang, Plas, David R, Guan, Jun-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651293/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.923
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