EXTH-53. A BRAIN-PENETRANT MICROTUBULE-TARGETING AGENT THAT DISRUPTS HALLMARKS OF GLIOMA TUMORIGENESIS

Most cancer therapeutics developed to date are excluded from the brain and are therefore ineffective in treating glioma, the most devastating type of brain cancer in adults. Microtubule targeting agents (MTAs) are indispensable medicines to treat a wide range of solid and hematopoietic tumors, and e...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Horne, Eric, Vicente Ruiz, Juan J, Cimino, Patrick, Jung, Erik, Xu, Cong, Diaz, Philippe, Hamel, Ernest, Kumasaka, Debra K, Wagenbach, Michael J, Winkler, Frank, Wordeman, Linda G, Holland, Eric, Stella, Nephi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Preclinical Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650914/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.407
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