EXTH-53. A BRAIN-PENETRANT MICROTUBULE-TARGETING AGENT THAT DISRUPTS HALLMARKS OF GLIOMA TUMORIGENESIS

Most cancer therapeutics developed to date are excluded from the brain and are therefore ineffective in treating glioma, the most devastating type of brain cancer in adults. Microtubule targeting agents (MTAs) are indispensable medicines to treat a wide range of solid and hematopoietic tumors, and e...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Horne, Eric, Vicente Ruiz, Juan J, Cimino, Patrick, Jung, Erik, Xu, Cong, Diaz, Philippe, Hamel, Ernest, Kumasaka, Debra K, Wagenbach, Michael J, Winkler, Frank, Wordeman, Linda G, Holland, Eric, Stella, Nephi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Preclinical Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650914/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.407
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