Human yolk sac-like haematopoiesis generates RUNX1-, GFI1- and/or GFI1B-dependent blood and SOX17-positive endothelium

The genetic regulatory network controlling early fate choices during human blood cell development are not well understood. We used human pluripotent stem cell reporter lines to track the development of endothelial and haematopoietic populations in an in vitro model of human yolk-sac development. We...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Development
Main Authors: Bruveris, Freya F., Ng, Elizabeth S., Leitoguinho, Ana Rita, Motazedian, Ali, Vlahos, Katerina, Sourris, Koula, Mayberry, Robyn, McDonald, Penelope, Azzola, Lisa, Davidson, Nadia M., Oshlack, Alicia, Stanley, Edouard G., Elefanty, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2020
Assuntos:
Human Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648599/
https://ncbi.nlm.nih.gov/pubmed/33028609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.193037
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares