Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development

Gfi1 is a transcriptional repressor essential for haematopoiesis and inner ear development. It shares with its paralogue Gfi1b an amino-terminal SNAG repressor domain and six carboxy-terminal zinc-finger motifs, but differs from Gfi1b in sequences separating these domains. Here, we describe two knoc...

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Autores principales: Fiolka, Katharina, Hertzano, Ronna, Vassen, Lothar, Zeng, Hui, Hermesh, Orit, Avraham, Karen B, Dührsen, Ulrich, Möröy, Tarik
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
Materias:
Scientific Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456886/
https://ncbi.nlm.nih.gov/pubmed/16397623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400618
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